Walk on the Wild Side: The Best of Lou Reed is the first greatest hits compilation by Lou Reed, formerly of The Velvet Underground. It was issued by RCA Records after Reed's first contract with them ended in 1976. Issued on compact disc on October 25, 1990. The album cover features photos by Mick Rock of Reed and then-girlfriend Rachel. 
"Walk on the Wild Side" is a song by Lou Reed from his second solo album, Transformer (1972). It was produced by David Bowie and Mick Ronson, and released as a double A-side with "Perfect Day". The song received wide radio coverage, despite its touching on taboo topics such as transsexuality, drugs, male prostitution, and oral sex. In the United States, RCA released the single using an edited version of the song without the reference to oral sex.